PGS (Preimplantation Genetic Screening)
PGS (Preimplantation Genetic Screening)
Shaping Tomorrow’s Healthy Generations With PGS
A 2021 study on preimplantation genetic testing has been reported to have a high accuracy rate of about 98%. Preimplantation Genetic Screening (PGS) is a specialised procedure used in assisted reproductive technology to check embryos for genetic flaws before implantation. Known for its complete assistance and PGS expertise, the Vizag IVF Centre helps people and couples worldwide on their quest for a healthy pregnancy and delivery.
A Run-Through of Preimplantation Genetic Screening (PGS)
Ovarian Stimulation
The woman is subjected to regulated ovarian stimulation in order to produce a large number of eggs. Injections of hormones are used to increase the likelihood of a fertilised egg.
Egg Retrieval
When the eggs are ready, a minimally invasive procedure called transvaginal ultrasound-guided aspiration removes them from the woman’s ovaries.
Fertilisation
In a lab setting, the retrieved eggs are subsequently fertilised with the partner’s or donor’s sperm. This can be done using intracytoplasmic sperm injection (ICSI), in which one sperm is directly injected into each egg, or standard IVF, in which the eggs and sperm are mixed together in a culture dish.
Embryo Development
The fertilised eggs—now referred to as embryos—are cultured in the lab for a number of days under precisely regulated circumstances. As a result, the embryos can grow and mature to a certain extent.
Embryo Biopsy
Several cells are gently extracted from each embryo at the proper developmental stage. On days 5 or 6, when an embryo is generally developed, the operation known as an embryo biopsy is carried out.
Genetic Analysis
The cells collected from the embryo biopsy are examined for chromosomal abnormalities or specific genetic diseases. Advanced methods, such as polymerase chain reaction (PCR) or next-generation sequencing (NGS), are used in this investigation.
Selection of Healthy Embryos
The outcomes of the genetic study make it possible to identify embryos free of the targeted genetic defects. These healthy embryos are chosen to be implanted into the uterus of the woman.
Embryo Transfer
A tiny catheter is used to insert the chosen embryos into the woman’s uterus. Typically, this procedure is painless and requires no anaesthetic. The age of the woman and the quality of the embryos are two of the many variables that affect how many embryos are transferred.
Cryopreservation
If more viable embryos are available than can be transferred in the first cycle, they can be cryopreserved (frozen) for later use, allowing for successive transfer attempts without the need for more ovarian stimulation.
Contact Vizag for Preimplantation Genetic Screening (PGS)
Preimplantation Genetic Screening lowers the possibility of chromosomal abnormalities or genetic diseases in the offspring while also increasing the likelihood of successful implantation. Couples at high risk of passing on specific genetic disorders or those who frequently lose pregnancies can benefit the most from it. Vizag IVF Centre plays a crucial part in assisting individuals and couples globally to build healthy families by providing this cutting-edge screening method. Contact Vizag to place a query 24/7 on our website or visit our centres located in Visakhapatnam, Gajuwaka, Srikakulam, & Viziangaram.
